Interacting Targets of the Farnesyl of Transducin γ-Subunit

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Interacting Targets of the Farnesyl of Transducin γ-Subunit

G protein gamma-subunits are isoprenylated and carboxyl methylated at the C-terminal cysteine residue, and the set of the posttranslational modifications is indispensable for the function of the photoreceptor G protein transducin (Talpha/Tbetagamma). To explore farnesyl-mediated molecular interactions, we investigated molecular targets of a Tbetagamma analogue that was engineered to have a phot...

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ژورنال

عنوان ژورنال: Biochemistry

سال: 2008

ISSN: 0006-2960,1520-4995

DOI: 10.1021/bi800359h